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PNC-27

PNC-27

Minimum order 2 vials or 2 pens — delivery in 2 weeks
p53-derived peptide that targets HDM-2 on the cell membrane: in vitro it was selectively cytotoxic to K562 leukemia cells expressing HDM-2, with no effect on normal lymphocytes.

In vitro, PNC-27 was selectively cytotoxic to K562 leukemia cells with HDM-2 on the membrane 1.

On normal lymphocytes, no effect — the selectivity is the finding.

No kill rate is given, only the selective action compared with normal cells.

What we don't know: behavior in a living organism, safety, dose.

Research use only — nothing to do with therapeutic use.

Sources — 1 published study
  1. Sarafraz-Yazdi E, et al. PNC-27 induces tumor cell necrosis dependent on HDM-2. Med Oncol. 2014;31(9):152.

Imagine a marksman who sees only the target, never the innocent bystander next to it!

PNC-27 selectively hit K562 leukemia cells with HDM-2 on the membrane, leaving normal lymphocytes untouched, in vitro 1 — precision in a dish!

A lab finding, not a treatment — let's say it plainly.

The peptide's purity? That's where we never play around.

What we don't know: a living organism, humans. Research use only — and we mean it!

Sources — 1 published study
  1. Sarafraz-Yazdi E, et al. PNC-27 induces tumor cell necrosis dependent on HDM-2. Med Oncol. 2014;31(9):152.

K562 leukemia cells with HDM-2 on the membrane — target. Normal lymphocytes — untouched. In vitro, clean 1.

Selectivity, not a mass attack. That's what the data show.

No promise of treatment — that's not how we play, ever.

Everything we sell is for research, purity certified.

What we don't know: in vivo, humans. Research use only, pure.

Sources — 1 published study
  1. Sarafraz-Yazdi E, et al. PNC-27 induces tumor cell necrosis dependent on HDM-2. Med Oncol. 2014;31(9):152.

Frequently asked questions

Which packs is PNC-27 available in?

Vial: 5 mg vial, 10 mg vial · Pens: 1 × 5 mg pen, 1 × 10 mg pen.

Is PNC-27 in stock?

We don't keep it in stock — it's ordered in: minimum 2 items (vials or pens) from the special-order products, with free shipping, and it arrives in about 2 weeks.

How much is shipping?

€3 shipping + €3 cash-on-delivery fee. For orders of 2 vials or pens or more, shipping and the cash-on-delivery fee are free. Delivery time depends on the courier.

How do I pay?

Cash on delivery, paid to the courier when it arrives. For an electronic money transfer (PayPal, Revolut, Wise, crypto), email us for the details: ellinikapeptidia@gmail.com

Can I return it?

Yes: you have a 14-day right of withdrawal from delivery, as long as the seal is intact. Return costs are yours, unless the product was faulty or wrong. Terms of Use

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