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SS-31

SS-31 (Elamipretide)

Minimum order 2 vials or 2 pens — delivery in 2 weeks
Not a broad-spectrum antioxidant — it binds to a specific lipid in the inner mitochondrial membrane, cardiolipin. With 168 weeks of data in Barth syndrome.

Category VI — Mitochondria & Longevity 🧮 Reconstitution calculator €99 – €241 from €79.20 to €192.80

SS-31 (elamipretide) isn't a general antioxidant — it binds to a specific site in the mitochondrion.

It concentrates in the inner mitochondrial membrane and binds to cardiolipin, the lipid that keeps the respiratory chain complexes assembled.

In Barth syndrome, a genetic disease where the defect lies precisely in cardiolipin, the 168-week open-label extension showed the six-minute walk improving by 96.1 meters (P = 0.003), along with better fatigue scores and cardiac volumes 1.

In a broader myopathy population, where the defect isn't located in cardiolipin, the available evidence is more limited — a 24-week trial didn't meet its two primary endpoints 2. The molecule's target looks narrow.

Research-use product. Lyophilized; refrigerate after reconstitution, protect from light, roll instead of shaking.

Sources — 2 published studies
  1. Thompson WR, Manuel R, Abbruscato A, et al. Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER. Genet Med. 2024;26(7):101138. doi:10.1016/j.gim.2024.101138
  2. Karaa A, et al. Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial. Neurology. 2023;101(3):e238-e252. doi:10.1212/WNL.0000000000207402

Think of the mitochondrion as your cell's power plant — and SS-31 as something that goes straight to the heart of the plant.

It binds to cardiolipin, the scaffold lipid that keeps the energy production chains standing inside the mitochondrion.

In Barth syndrome, where exactly this lipid is defective, a long 168-week study recorded a walking improvement of 96.1 meters (P = 0.003), along with less fatigue 1.

It's a molecule with a narrow, specific target — in populations where the problem lies elsewhere, the evidence remains more limited 2. We say so because honesty is part of care too.

Research-use product. Fridge after reconstitution, away from light, roll never shake.

Sources — 2 published studies
  1. Thompson WR, Manuel R, Abbruscato A, et al. Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER. Genet Med. 2024;26(7):101138. doi:10.1016/j.gim.2024.101138
  2. Karaa A, et al. Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial. Neurology. 2023;101(3):e238-e252. doi:10.1212/WNL.0000000000207402

It doesn't scavenge free radicals. It binds to one specific lipid.

That's what sets it apart from every “antioxidant” you've seen. SS-31 — pharmaceutically elamipretide — concentrates in the inner mitochondrial membrane and binds to cardiolipin, the lipid that keeps the respiratory chain complexes assembled. When cardiolipin breaks down, energy production breaks down with it.

Its target is narrow and specific — and that's exactly where it shows its value.

The strong data point, with a biomarker: TAZPOWER, in Barth syndrome — a genetic disease where the defect is precisely in cardiolipin. In the 168-week open-label extension, the six-minute walk improved cumulatively by 96.1 meters (P = 0.003), fatigue fell at every time point, three-dimensional left ventricular volumes improved — and the cardiolipin MLCL/CL ratio moved in step with the clinical picture 1.

Why this matters more than a promise: the molecule works where the problem is cardiolipin. Targeted, not “for everything” — and that focus is its value.

Everything we sell is for research — clean, with certified purity, stored properly.

Sources — 1 published study
  1. Thompson WR, Manuel R, Abbruscato A, et al. Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER. Genet Med. 2024;26(7):101138. doi:10.1016/j.gim.2024.101138

Frequently asked questions

Which packs is SS-31 (Elamipretide) available in?

Vial: 10 mg vial, 50 mg vial · Pens: 1 × 10 mg pen, 1 × 50 mg pen.

Is SS-31 (Elamipretide) in stock?

We don't keep it in stock — it's ordered in: minimum 2 items (vials or pens) from the special-order products, with free shipping, and it arrives in about 2 weeks.

How much is shipping?

€3 shipping + €3 cash-on-delivery fee. For orders of 2 vials or pens or more, shipping and the cash-on-delivery fee are free. Delivery time depends on the courier.

How do I pay?

Cash on delivery, paid to the courier when it arrives. For an electronic money transfer (PayPal, Revolut, Wise, crypto), email us for the details: ellinikapeptidia@gmail.com

Can I return it?

Yes: you have a 14-day right of withdrawal from delivery, as long as the seal is intact. Return costs are yours, unless the product was faulty or wrong. Terms of Use

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